Select your language

Medienmitteilung: pdfSwiss-TB-Award-2018.pdf87.13 kB29/03/2019, 12:43

Die Schweizerische Stiftung für Tuberkuloseforschung vergibt seit 2002 jedes Jahr den mit CHF 10'000 dotierten Swiss TB Award für herausragende Arbeiten von Schweizer Forschenden. Die diesjährigen Preisträgerinnen sind Frau Kathrin Zürcher und Frau Marie Ballif vom ISPM in Bern mit ihrer soeben in der Zeitschrift Lancet publizierten wichtigen Arbeit über die Bedeutung einer korrektiven Testung der Tuberkuloseerreger auf Medikamentenresistenz auf die Behandlungsergebnisse. Dies hat insbesondere bei mehrfachresistenten (MDR) oder gänzlich resistenten (XDR) Tuberkulosekranken einen entscheidenden Einfluss auf ihr Überleben.

The study, which was published just on the World TB Day 2019 in Lancet Infect Dis, resulted from a large collaborative project between the Institute of Social and Preventive Medicine (ISPM) of the University of Bern, the Swiss Tropical and Public Health Institute in Basel and the Institute of Medical Microbiology (Swiss National Center for Mycobacteria) in Zurich.
This project was funded by the Swiss National Science Foundation and the US National Institutes of Health. The overarching aim was to compile a Mycobacterium tuberculosis strain collection from HIV co-infected and HIV negative individuals in eight low- and middle-income countries worldwide, and to study the mechanisms underlying M. tuberculosis drug resistance. We reported on the challenges to diagnose and treat drug-resistant TB in resource-limited settings. Inaccurate drug susceptibility tests (DST) leading to inappropriate treatment contributes to the high mortality associated with drug-resistant TB. Local access to accurate and rapid DST of anti-TB drugs is required to improve outcomes in patients with drug-resistant TB.

Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multi-centre cohort study
Kathrin Zürcher , Marie Ballif, Lukas Fenner, Sonia Borrell, Peter M. Keller, Joachim Gnokoro, Olivier Marcy, Marcel Yotebieng, Lameck Diero, E. Jane Carter,…...
Sebastien Gagneux, Erik C. Böttger and Matthias Egger, on behalf of the
International Epidemiology Databases to Evaluate AIDS consortium
Lancet Infect Dis 2019; 19:298-307

We use cookies

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.